The notions of active ingredient and vector (4)
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| The development of biotechnologies in the 1980s for the massive production of hyaluronic acid (initially obtained from cockscomb), esters, surfactant or active agents [1]
(Beta-glucanes and yeast polysaccharides) changed the situation. Due to lower costs and to large-scale preparation, rare or new products became more widely available. |
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Phase diagram of CO2 (carbon dioxide), by Ben Finney Mark Jacobs. X axis is temperature in kelvin; Y axis is pressure in bar. In the diagram 4 is
domain of apparition of the supercritic state
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| Source : Wikimedia. |
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Details of an advertising for Flavex products. Parfums, Cosmétiques, Arômes, 1992.
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| BIU Santé Pharmacie : cote P 10167. |
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Supercritical CO2 apparatus.
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| © LVMH Recherche. |
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In the 1990s, new technologies of clean extraction (as supercritical CO2) were perfected. They produced no residual solvents or used cold (lyophilization, cryogenic treatment), and allowed the production of vegetal extracts
that were very close to the original product.
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Lyophilizator. Stokes system. Traité de lyophilisation, par Louis Rey et collaborateurs. Paris: Hermann, 1960.
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| BIU Santé Pharmacie : cote 110670 |
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Freeze dryer . Progrès récents en lyophilisation, par Louis Rey et collaborateurs. Paris: Hermann, 1962.
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| BIU Santé Pharmacie : cote : 11794 |
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Freeze dryer. Progrès récents en lyophilisation, par Louis Rey et collaborateurs. Paris: Hermann, 1962.
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| BIU Santé Pharmacie : cote : 11794 |
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